Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDH3A1BA-20-REGO | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-REGR | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-GROR | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDH3A1BA-20-AQOR | 20 (40 μL) | 200 μL |
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Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Gene Symbol : ALDH3A1
Gene Name : Aldehyde dehydrogenase 3 family member A1
Chromosome : CHR 17: 197,484,32-197,379,83
Locus : 17p11.2
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