The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| E4F1BA-20-REGO | 20 (40 μL) | 200 μL |
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| E4F1BA-20-REGR | 20 (40 μL) | 200 μL |
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| E4F1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| E4F1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| E4F1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| E4F1BA-20-GROR | 20 (40 μL) | 200 μL |
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| E4F1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| E4F1BA-20-AQOR | 20 (40 μL) | 200 μL |
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The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]
Gene Symbol : E4F1
Gene Name : E4F transcription factor 1
Chromosome : CHR 16: 222,348,7-223,574,1
Locus : 16p13.3
Alt. Genes : ZNF263
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