This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EVPLBA-20-REGO | 20 (40 μL) | 200 μL |
|
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| EVPLBA-20-REGR | 20 (40 μL) | 200 μL |
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| EVPLBA-20-ORGR | 20 (40 μL) | 200 μL |
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| EVPLBA-20-GOGR | 20 (40 μL) | 200 μL |
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| EVPLBA-20-GRRE | 20 (40 μL) | 200 μL |
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| EVPLBA-20-GROR | 20 (40 μL) | 200 μL |
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| EVPLBA-20-GRGO | 20 (40 μL) | 200 μL |
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| EVPLBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against the encoded protein. [provided by RefSeq, Jul 2016]
Gene Symbol : EVPL
Gene Name : Envoplakin
Chromosome : CHR 17: 760,274,51-760,068,44
Locus : 17q25.1
Alt. Genes : FEM1B
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