F2 Break Apart FISH Probe

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
F2BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
F2BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Gene Details

Gene Symbol : F2

Gene Name : Coagulation factor II, thrombin

Chromosome : CHR 11: 467,191,65-467,395,07

Locus : 11p11.2

Alt. Genes : LRPPRC

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