Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBLN1BA-20-REGO | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-REGR | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-GROR | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| FBLN1BA-20-AQOR | 20 (40 μL) | 200 μL |
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Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]
Gene Symbol : FBLN1
Gene Name : Fibulin 1
Chromosome : CHR 22: 455,028,38-456,011,33
Locus : 22q13.31
Alt. Genes : PREB
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