This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FCARBA-20-REGO | 20 (40 μL) | 200 μL |
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| FCARBA-20-REGR | 20 (40 μL) | 200 μL |
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| FCARBA-20-ORGR | 20 (40 μL) | 200 μL |
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| FCARBA-20-GOGR | 20 (40 μL) | 200 μL |
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| FCARBA-20-GRRE | 20 (40 μL) | 200 μL |
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| FCARBA-20-GROR | 20 (40 μL) | 200 μL |
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| FCARBA-20-GRGO | 20 (40 μL) | 200 μL |
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| FCARBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : FCAR
Gene Name : Fc fragment of IgA receptor
Chromosome : CHR 19: 548,740,92-548,914,19
Locus : 19q13.42
Alt. Genes : SEMA4D
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