The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FCGR2BBA-20-REGO | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-REGR | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-ORGR | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-GROR | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| FCGR2BBA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Symbol : FCGR2B
Gene Name : Fc fragment of IgG receptor IIb
Chromosome : CHR 1: 161,647,242-161,678,653
Locus : 1q23.3
Alt. Genes : STUB1
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