This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FGD1BA-20-REGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-GROR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGD1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
Request Pricing |
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. [provided by RefSeq, Jul 2017]
Gene Symbol : FGD1
Gene Name : FYVE, RhoGEF and PH domain containing 1
Chromosome : CHR X: 544,961,65-544,454,53
Locus : Xp11.22
Alt. Genes : BCAP31
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.