This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FGRBA-20-REGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-REGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-ORGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-GOGR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-GRRE | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-GROR | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-GRGO | 20 (40 μL) | 200 μL |
|
Request Pricing |
| FGRBA-20-AQOR | 20 (40 μL) | 200 μL |
|
Request Pricing |
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : FGR
Gene Name : FGR proto-oncogene, Src family tyrosine kinase
Chromosome : CHR 1: 276,355,60-276,122,88
Locus : 1p35.3
Alt. Genes : CLEC3A
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.