The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FOLR1BA-20-REGO | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-REGR | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-GROR | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| FOLR1BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : FOLR1
Gene Name : Folate receptor 1
Chromosome : CHR 11: 721,895,57-721,963,22
Locus : 11q13.4
Alt. Genes : PSMD14
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