Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GCLMBA-20-REGO | 20 (40 μL) | 200 μL |
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| GCLMBA-20-REGR | 20 (40 μL) | 200 μL |
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| GCLMBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GCLMBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GCLMBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GCLMBA-20-GROR | 20 (40 μL) | 200 μL |
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| GCLMBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GCLMBA-20-AQOR | 20 (40 μL) | 200 μL |
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Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Symbol : GCLM
Gene Name : Glutamate-cysteine ligase modifier subunit
Chromosome : CHR 1: 939,095,97-938,851,98
Locus : 1p22.1
Alt. Genes : FEM1B
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