The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GNA11BA-20-REGO | 20 (40 μL) | 200 μL |
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| GNA11BA-20-REGR | 20 (40 μL) | 200 μL |
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| GNA11BA-20-ORGR | 20 (40 μL) | 200 μL |
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| GNA11BA-20-GOGR | 20 (40 μL) | 200 μL |
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| GNA11BA-20-GRRE | 20 (40 μL) | 200 μL |
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| GNA11BA-20-GROR | 20 (40 μL) | 200 μL |
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| GNA11BA-20-GRGO | 20 (40 μL) | 200 μL |
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| GNA11BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]
Gene Symbol : GNA11
Gene Name : G protein subunit alpha 11
Chromosome : CHR 19: 309,440,9-312,400,1
Locus : 19p13.3
Alt. Genes : PLXNC1
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