GRIN2A Break Apart FISH Probe

This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
GRIN2ABA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
GRIN2ABA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Gene Details

Gene Symbol : GRIN2A

Gene Name : Glutamate ionotropic receptor NMDA type subunit 2A

Chromosome : CHR 16: 101,833,63-975,340,3

Locus : 16p13.2

Alt. Genes : RBM12

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