This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GUCY2CBA-20-REGO | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-REGR | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-GROR | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GUCY2CBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]
Gene Symbol : GUCY2C
Gene Name : Guanylate cyclase 2C
Chromosome : CHR 12: 146,966,24-146,126,31
Locus : 12p12.3
Alt. Genes : OPTN
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