This gene is nonfunctional in humans and other primates. In most mammalian species the corresponding gene encodes L-gulono-gamma-lactone oxidase which catalyzes the last step of ascorbic acid biosynthesis. The human gene is a remnant that lacks five of twelve exons found in functional rodent genes. The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GULOPBA-20-REGO | 20 (40 μL) | 200 μL |
|
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| GULOPBA-20-REGR | 20 (40 μL) | 200 μL |
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| GULOPBA-20-ORGR | 20 (40 μL) | 200 μL |
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| GULOPBA-20-GOGR | 20 (40 μL) | 200 μL |
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| GULOPBA-20-GRRE | 20 (40 μL) | 200 μL |
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| GULOPBA-20-GROR | 20 (40 μL) | 200 μL |
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| GULOPBA-20-GRGO | 20 (40 μL) | 200 μL |
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| GULOPBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene is nonfunctional in humans and other primates. In most mammalian species the corresponding gene encodes L-gulono-gamma-lactone oxidase which catalyzes the last step of ascorbic acid biosynthesis. The human gene is a remnant that lacks five of twelve exons found in functional rodent genes. The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]
Gene Symbol : GULOP
Gene Name : Gulonolactone (L-) oxidase, pseudogene
Chromosome : CHR 8: 275,776,10-275,890,72
Locus : 8p21.1
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