HMGB2 Break Apart FISH Probe

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
HMGB2BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
HMGB2BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : HMGB2

Gene Name : High mobility group box 2

Chromosome : CHR 4: 173,334,443-173,331,375

Locus : 4q34.1

Alt. Genes : CELA3A

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