In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HOXA5BA-20-REGO | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-REGR | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-ORGR | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-GOGR | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-GRRE | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-GROR | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-GRGO | 20 (40 μL) | 200 μL |
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| HOXA5BA-20-AQOR | 20 (40 μL) | 200 μL |
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In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]
Gene Symbol : HOXA5
Gene Name : Homeobox A5
Chromosome : CHR 7: 271,436,67-271,410,51
Locus : 7p15.2
Alt. Genes : CELA3A
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