This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HOXB6BA-20-REGO | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-REGR | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-ORGR | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-GOGR | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-GRRE | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-GROR | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-GRGO | 20 (40 μL) | 200 μL |
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| HOXB6BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]
Gene Symbol : HOXB6
Gene Name : Homeobox B6
Chromosome : CHR 17: 486,049,91-485,957,35
Locus : 17q21.32
Alt. Genes : TRIM28
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