This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HOXD8BA-20-REGO | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-REGR | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-ORGR | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-GOGR | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-GRRE | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-GROR | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-GRGO | 20 (40 μL) | 200 μL |
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| HOXD8BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Gene Symbol : HOXD8
Gene Name : Homeobox D8
Chromosome : CHR 2: 176,129,693-176,132,694
Locus : 2q31.1
Alt. Genes : OPTN
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