This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HPRBA-20-REGO | 20 (40 μL) | 200 μL |
|
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| HPRBA-20-REGR | 20 (40 μL) | 200 μL |
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| HPRBA-20-ORGR | 20 (40 μL) | 200 μL |
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| HPRBA-20-GOGR | 20 (40 μL) | 200 μL |
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| HPRBA-20-GRRE | 20 (40 μL) | 200 μL |
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| HPRBA-20-GROR | 20 (40 μL) | 200 μL |
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| HPRBA-20-GRGO | 20 (40 μL) | 200 μL |
|
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| HPRBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]
Gene Symbol : HPR
Gene Name : Haptoglobin-related protein
Chromosome : CHR 16: 720,632,25-720,772,45
Locus : 16q22.2
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