The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGFALSBA-20-REGO | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-REGR | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-ORGR | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-GOGR | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-GRRE | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-GROR | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-GRGO | 20 (40 μL) | 200 μL |
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| IGFALSBA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Symbol : IGFALS
Gene Name : Insulin like growth factor binding protein acid labile subunit
Chromosome : CHR 16: 179,490,7-179,041,2
Locus : 16p13.3
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