This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ILKBA-20-REGO | 20 (40 μL) | 200 μL |
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| ILKBA-20-REGR | 20 (40 μL) | 200 μL |
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| ILKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| ILKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ILKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ILKBA-20-GROR | 20 (40 μL) | 200 μL |
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| ILKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ILKBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Gene Symbol : ILK
Gene Name : Integrin linked kinase
Chromosome : CHR 11: 660,370,7-661,087,3
Locus : 11p15.4
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