IRF1 Break Apart FISH Probe

The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
IRF1BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
IRF1BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol : IRF1

Gene Name : Interferon regulatory factor 1

Chromosome : CHR 5: 132,490,788-132,481,608

Locus : 5q31.1

Alt. Genes : OPTN

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