This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IRF3BA-20-REGO | 20 (40 μL) | 200 μL |
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| IRF3BA-20-REGR | 20 (40 μL) | 200 μL |
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| IRF3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| IRF3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| IRF3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| IRF3BA-20-GROR | 20 (40 μL) | 200 μL |
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| IRF3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| IRF3BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Gene Symbol : IRF3
Gene Name : Interferon regulatory factor 3
Chromosome : CHR 19: 496,658,74-496,595,68
Locus : 19q13.33
Alt. Genes : RASA4
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