ITGAE Break Apart FISH Probe

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ITGAEBA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ITGAEBA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : ITGAE

Gene Name : Integrin subunit alpha E

Chromosome : CHR 17: 380,376,5-371,462,4

Locus : 17p13.2

Alt. Genes : ATP6AP2

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