Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IVDBA-20-REGO | 20 (40 μL) | 200 μL |
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| IVDBA-20-REGR | 20 (40 μL) | 200 μL |
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| IVDBA-20-ORGR | 20 (40 μL) | 200 μL |
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| IVDBA-20-GOGR | 20 (40 μL) | 200 μL |
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| IVDBA-20-GRRE | 20 (40 μL) | 200 μL |
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| IVDBA-20-GROR | 20 (40 μL) | 200 μL |
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| IVDBA-20-GRGO | 20 (40 μL) | 200 μL |
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| IVDBA-20-AQOR | 20 (40 μL) | 200 μL |
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Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Gene Symbol : IVD
Gene Name : Isovaleryl-CoA dehydrogenase
Chromosome : CHR 15: 404,054,84-404,359,47
Locus : 15q15.1
Alt. Genes : MKRN3-AS1
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