The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| JAK3BA-20-REGO | 20 (40 μL) | 200 μL |
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| JAK3BA-20-REGR | 20 (40 μL) | 200 μL |
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| JAK3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| JAK3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| JAK3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| JAK3BA-20-GROR | 20 (40 μL) | 200 μL |
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| JAK3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| JAK3BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Gene Symbol : JAK3
Gene Name : Janus kinase 3
Chromosome : CHR 19: 178,480,70-178,247,81
Locus : 19p13.11
Alt. Genes : ABI2
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