This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNQ3BA-20-REGO | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-REGR | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-GROR | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNQ3BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Symbol : KCNQ3
Gene Name : Potassium voltage-gated channel subfamily Q member 3
Chromosome : CHR 8: 132,480,756-132,120,857
Locus : 8q24.22
Alt. Genes : OPTN
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