KDR Break Apart FISH Probe

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
KDRBA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
KDRBA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Gene Details

Gene Symbol : KDR

Gene Name : Kinase insert domain receptor

Chromosome : CHR 4: 551,255,94-550,782,58

Locus : 4q12

Alt. Genes : FRY

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