The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LMAN1BA-20-REGO | 20 (40 μL) | 200 μL |
|
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| LMAN1BA-20-REGR | 20 (40 μL) | 200 μL |
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| LMAN1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| LMAN1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| LMAN1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| LMAN1BA-20-GROR | 20 (40 μL) | 200 μL |
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| LMAN1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| LMAN1BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
Gene Symbol : LMAN1
Gene Name : Lectin, mannose binding 1
Chromosome : CHR 18: 593,592,75-593,278,22
Locus : 18q21.32
Alt. Genes : FEM1B
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