This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LMX1BBA-20-REGO | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-REGR | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-ORGR | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-GROR | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| LMX1BBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Symbol : LMX1B
Gene Name : LIM homeobox transcription factor 1 beta
Chromosome : CHR 9: 126,614,442-126,701,031
Locus : 9q33.3
Alt. Genes : RBM12
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