The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XRCC6BA-20-REGO | 20 (40 μL) | 200 μL |
|
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| XRCC6BA-20-REGR | 20 (40 μL) | 200 μL |
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| XRCC6BA-20-ORGR | 20 (40 μL) | 200 μL |
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| XRCC6BA-20-GOGR | 20 (40 μL) | 200 μL |
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| XRCC6BA-20-GRRE | 20 (40 μL) | 200 μL |
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| XRCC6BA-20-GROR | 20 (40 μL) | 200 μL |
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| XRCC6BA-20-GRGO | 20 (40 μL) | 200 μL |
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| XRCC6BA-20-AQOR | 20 (40 μL) | 200 μL |
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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Gene Symbol : XRCC6
Gene Name : X-ray repair cross complementing 6
Chromosome : CHR 22: 416,211,62-416,640,47
Locus : 22q13.2
Alt. Genes : ZNF263
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