ALCAM Summary

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]

ALCAM Details

Gene Symbol : ALCAM

Gene Name : Activated leukocyte cell adhesion molecule

Chromosome : CHR 3: 105,366,712-105,576,912

Locus : 3q13.11

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SH3KBP1 Summary

This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

SH3KBP1 Details

Gene Symbol : SH3KBP1

Gene Name : SH3 domain containing kinase binding protein 1

Chromosome : CHR X: 198,876,25-195,339,64

Locus : Xp22.12

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