| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDH1A1-FXYD1-20-RERE | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-REOR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-REGO | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-REGR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-OROR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-ORGR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GORE | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GROR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDH1A1-FXYD1-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
Gene Symbol : ALDH1A1
Gene Name : Aldehyde dehydrogenase 1 family member A1
Chromosome : CHR 9: 729,533,16-729,006,61
Locus : 9q21.13
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008]
Gene Symbol : FXYD1
Gene Name : FXYD domain containing ion transport regulator 1
Chromosome : CHR 19: 351,372,06-351,430,54
Locus : 19q13.12
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