| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDH2-LRBA-20-RERE | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-REOR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-REGO | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-REGR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-OROR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-ORGR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GORE | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GROR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDH2-LRBA-20-AQAQ | 20 (40 μL) | 200 μL |
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This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]
Gene Symbol : ALDH2
Gene Name : Aldehyde dehydrogenase 2 family (mitochondrial)
Chromosome : CHR 12: 111,766,886-111,809,984
Locus : 12q24.12
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Symbol : LRBA
Gene Name : LPS responsive beige-like anchor protein
Chromosome : CHR 4: 151,015,724-150,264,514
Locus : 4q31.3
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