BCR-ABL Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
BCR-ABL-20-RERE 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-REOR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-REGO 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-REGR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-OROR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GORE 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GROR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
BCR-ABL-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

BCR Summary

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

BCR Details

Gene Symbol : BCR

Gene Name : BCR, RhoGEF and GTPase activating protein

Chromosome : CHR 22: 231,803,64-233,180,36

Locus : 22q11.23


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