SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
BCR-ABL-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
BCR-ABL-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : BCR
Gene Name : BCR, RhoGEF and GTPase activating protein
Chromosome : CHR 22: 231,803,64-233,180,36
Locus : 22q11.23
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