TBCE Summary

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

TBCE Details

Gene Symbol : TBCE

Gene Name : Tubulin folding cofactor E

Chromosome : CHR 1: 235,367,359-235,448,967

Locus : 1q42.3

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SIPA1L2 Summary

This gene encodes a member of the signal-induced proliferation-associated 1 like family. Members of this family contain a GTPase activating domain, a PDZ domain and a C-terminal coiled-coil domain with a leucine zipper. A similar protein in rat acts as a GTPases for the small GTPase Rap. [provided by RefSeq, Sep 2015]

SIPA1L2 Details

Gene Symbol : SIPA1L2

Gene Name : Signal induced proliferation associated 1 like 2

Chromosome : CHR 1: 232,630,490-232,397,964

Locus : 1q42.2

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