SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TBL1XR1-CACNA1C-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
TBL1XR1-CACNA1C-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
Gene Symbol : CACNA1C
Gene Name : Calcium voltage-gated channel subunit alpha1 C
Chromosome : CHR 12: 196,967,6-269,794,8
Locus : 12p13.33
This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]
Gene Symbol : TBL1XR1
Gene Name : Transducin beta like 1 X-linked receptor 1
Chromosome : CHR 3: 177,197,356-177,019,354
Locus : 3q26.32
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