TBL1XR1-CACNA1C Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
TBL1XR1-CACNA1C-20-RERE 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-REOR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-REGO 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-REGR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-OROR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GORE 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GROR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
TBL1XR1-CACNA1C-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

CACNA1C Summary

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]

CACNA1C Details

Gene Symbol : CACNA1C

Gene Name : Calcium voltage-gated channel subunit alpha1 C

Chromosome : CHR 12: 196,967,6-269,794,8

Locus : 12p13.33


TBL1XR1 Summary

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]

TBL1XR1 Details

Gene Symbol : TBL1XR1

Gene Name : Transducin beta like 1 X-linked receptor 1

Chromosome : CHR 3: 177,197,356-177,019,354

Locus : 3q26.32


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