TBXAS1 Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

TBXAS1 Details

Gene Symbol : TBXAS1

Gene Name : Thromboxane A synthase 1

Chromosome : CHR 7: 139,778,247-140,020,324

Locus : 7q34

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TOMM7 Summary

This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]

TOMM7 Details

Gene Symbol : TOMM7

Gene Name : Translocase of outer mitochondrial membrane 7

Chromosome : CHR 7: 228,228,51-228,126,31

Locus : 7p15.3

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