| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TCF3-AP3D1-20-RERE | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-REOR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-REGO | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-REGR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-OROR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-ORGR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GORE | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GROR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF3-AP3D1-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
Gene Symbol : TCF3
Gene Name : Transcription factor 3
Chromosome : CHR 19: 165,258,9-160,928,9
Locus : 19p13.3
The protein encoded by this gene is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Defects in this gene are a cause of a new type of Hermansky-Pudlak syndrome. [provided by RefSeq, Feb 2017]
Gene Symbol : AP3D1
Gene Name : Adaptor related protein complex 3 delta 1 subunit
Chromosome : CHR 19: 215,161,9-210,098,7
Locus : 19p13.3
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