ACTG2 Summary

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]

ACTG2 Details

Gene Symbol : ACTG2

Gene Name : Actin, gamma 2, smooth muscle, enteric

Chromosome : CHR 2: 738,929,65-739,196,52

Locus : 2p13.1

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TET3 Summary

Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM, Nov 2010]

TET3 Details

Gene Symbol : TET3

Gene Name : Tet methylcytosine dioxygenase 3

Chromosome : CHR 2: 739,820,35-741,081,75

Locus : 2p13.1

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