IGF2BP3 Summary

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

IGF2BP3 Details

Gene Symbol : IGF2BP3

Gene Name : Insulin like growth factor 2 mRNA binding protein 3

Chromosome : CHR 7: 234,706,73-233,102,08

Locus : 7p15.3

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THADA Summary

This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]

THADA Details

Gene Symbol : THADA

Gene Name : THADA, armadillo repeat containing

Chromosome : CHR 2: 435,960,45-432,308,35

Locus : 2p21

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