NEDD9 Summary

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

NEDD9 Details

Gene Symbol : NEDD9

Gene Name : Neural precursor cell expressed, developmentally down-regulated 9

Chromosome : CHR 6: 113,823,47-111,832,97

Locus : 6p24.2

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TMLHE Summary

This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

TMLHE Details

Gene Symbol : TMLHE

Gene Name : Trimethyllysine hydroxylase, epsilon

Chromosome : CHR X: 155,612,960-155,489,006

Locus : Xq28

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