GNA14 Summary

This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]

GNA14 Details

Gene Symbol : GNA14

Gene Name : G protein subunit alpha 14

Chromosome : CHR 9: 776,483,15-774,230,78

Locus : 9q21.2

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TMTC2 Summary

The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

TMTC2 Details

Gene Symbol : TMTC2

Gene Name : Transmembrane and tetratricopeptide repeat containing 2

Chromosome : CHR 12: 826,869,51-831,348,67

Locus : 12q21.31

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