TNFAIP3 Summary

This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]

TNFAIP3 Details

Gene Symbol : TNFAIP3

Gene Name : TNF alpha induced protein 3

Chromosome : CHR 6: 137,866,316-137,883,313

Locus : 6q23.3

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IL26 Summary

This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008]

IL26 Details

Gene Symbol : IL26

Gene Name : Interleukin 26

Chromosome : CHR 12: 682,257,90-682,013,48

Locus : 12q15

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