| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNPO3-RCAN1-20-RERE | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-REOR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-REGO | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-REGR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-REAQ | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-ORRE | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-OROR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-ORGO | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-ORGR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GORE | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GOOR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GOGO | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GOGR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GRRE | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GROR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GRGO | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GRGR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-AQRE | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-AQOR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-AQGO | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-AQGR | 20 (40 μL) | 200 μL |
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| TNPO3-RCAN1-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Symbol : RCAN1
Gene Name : Regulator of calcineurin 1
Chromosome : CHR 21: 346,151,41-345,164,41
Locus : 21q22.12
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
Gene Symbol : TNPO3
Gene Name : Transportin 3
Chromosome : CHR 7: 129,055,172-128,954,179
Locus : 7q32.1
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