| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPT1-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-ORGR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| TPT1-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Gene Symbol : TPT1
Gene Name : Tumor protein, translationally-controlled 1
Chromosome : CHR 13: 453,412,83-453,334,70
Locus : 13q14.13
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Symbol : ARFGEF2
Gene Name : ADP ribosylation factor guanine nucleotide exchange factor 2
Chromosome : CHR 20: 489,217,20-490,366,92
Locus : 20q13.13
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