TPT1-MME Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
TPT1-MME-20-RERE 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-REOR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-REGO 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-REGR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-OROR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GORE 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GROR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
TPT1-MME-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

MME Summary

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]

MME Details

Gene Symbol : MME

Gene Name : Membrane metalloendopeptidase

Chromosome : CHR 3: 155,024,123-155,183,728

Locus : 3q25.2


TPT1 Summary

This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

TPT1 Details

Gene Symbol : TPT1

Gene Name : Tumor protein, translationally-controlled 1

Chromosome : CHR 13: 453,412,83-453,334,70

Locus : 13q14.13


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