TRAF2-CACNA1B Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
TRAF2-CACNA1B-20-RERE 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-REOR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-REGO 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-REGR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-OROR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GORE 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GROR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
TRAF2-CACNA1B-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

CACNA1B Summary

The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

CACNA1B Details

Gene Symbol : CACNA1B

Gene Name : Calcium voltage-gated channel subunit alpha1 B

Chromosome : CHR 9: 137,877,788-138,124,623

Locus : 9q34.3


TRAF2 Summary

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008]

TRAF2 Details

Gene Symbol : TRAF2

Gene Name : TNF receptor associated factor 2

Chromosome : CHR 9: 136,881,775-136,926,614

Locus : 9q34.3


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