SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TRAF2-CACNA1B-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
TRAF2-CACNA1B-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Symbol : CACNA1B
Gene Name : Calcium voltage-gated channel subunit alpha1 B
Chromosome : CHR 9: 137,877,788-138,124,623
Locus : 9q34.3
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : TRAF2
Gene Name : TNF receptor associated factor 2
Chromosome : CHR 9: 136,881,775-136,926,614
Locus : 9q34.3
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