| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRAF3-CDC42BPB-20-RERE | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-REOR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-REGO | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-REGR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-REAQ | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-ORRE | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-OROR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-ORGO | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-ORGR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GORE | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GOOR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GOGO | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GOGR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GRRE | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GROR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GRGO | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GRGR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-AQRE | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-AQOR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-AQGO | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-AQGR | 20 (40 μL) | 200 μL |
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| TRAF3-CDC42BPB-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]
Gene Symbol : TRAF3
Gene Name : TNF receptor associated factor 3
Chromosome : CHR 14: 102,777,478-102,911,499
Locus : 14q32.32
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]
Gene Symbol : CDC42BPB
Gene Name : CDC42 binding protein kinase beta
Chromosome : CHR 14: 103,057,404-102,932,378
Locus : 14q32.32
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